Inversin Antikörper (C-Term)

Produktnummer ABIN8103446

Der Kaninchen Polyklonal anti-Inversin Antikörper wird verwendet zum Nachweis von Inversin in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Inversin Antikörper (C-Term) (ABIN8103446)

Target: Inversin (INVS)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Inversin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Inversin Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: INVS Antibody - C-terminal region

Sequenz: ALLKAGADVN KTDHSQRTAL HLAAQKGNYR FMKLLLTRRA NWMQKDLEEM

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 86%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human INVS

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63318-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Inversin

Target: Inversin (INVS)

Andere Bezeichnung: INVS

Hintergrund:

Background Information: This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: inversin

Alternative Symbols: INV, NPH2, NPHP2

Protein Name: Inversin

Molekulargewicht: 117 kDa

Gen-ID: 27130

NCBI Accession: NP_055240

UniProt: Q9Y283