HMBS Antikörper (C-Term)

Produktnummer ABIN8102862

Der Kaninchen Polyklonal anti-HMBS Antikörper (ABIN8102862) detektiert spezifisch HMBS in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HMBS Antikörper (C-Term) (ABIN8102862)

Target: HMBS (Hydroxymethylbilane Synthase (HMBS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMBS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HMBS Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: HMBS Antibody - C-terminal region

Sequenz: VPAQHEDGPE DDPQLVGITA RNIPRGPQLA AQNLGISLAN LLLSKGAKNI

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HEM3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74562-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HMBS

Target: HMBS (Hydroxymethylbilane Synthase (HMBS))

Andere Bezeichnung: HMBS

Hintergrund:

Background Information: This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: hydroxymethylbilane synthase

Alternative Symbols: UPS, PBGD, PORC, PBG-D

Protein Name: porphobilinogen deaminase

Molekulargewicht: 39kDa

Gen-ID: 3145

UniProt: P08397