GBA2 Antikörper (Middle Region)

Produktnummer ABIN8101560

Der Kaninchen Polyklonal anti-GBA2 Antikörper (ABIN8101560) detektiert spezifisch GBA2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GBA2 Antikörper (Middle Region) (ABIN8101560)

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GBA2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: GBA2 Antibody - middle region

Sequenz: GTVWLEVLED SLPEELGRNM CHLRPTLRDY GRFGYLEGQE YRMYNTYDVH

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GBA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57499-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GBA2

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Andere Bezeichnung: GBA2

Hintergrund:

Background Information: This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.

Gene Name: glucosylceramidase beta 2

Alternative Symbols: AD035, SPG46, NLGase

Protein Name: Non-lysosomal glucosylceramidase

Molekulargewicht: 105 kDa

Gen-ID: 57704

NCBI Accession: NP_065995

UniProt: Q9HCG7