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ADAM32 Antikörper (AA 181-280) (HRP)

ADAM32 Reaktivität: Human, Maus WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN758885
  • Target Alle ADAM32 Antikörper anzeigen
    ADAM32 (ADAM Metallopeptidase Domain 32 (ADAM32))
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 181-280
    Reaktivität
    • 42
    • 19
    • 5
    • 4
    • 4
    • 4
    Human, Maus
    Wirt
    • 39
    • 2
    • 1
    Kaninchen
    Klonalität
    • 42
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADAM32 Antikörper ist konjugiert mit HRP
    Applikation
    • 42
    • 20
    • 13
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Pig,Horse,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ADAM32
    Isotyp
    IgG
    Top Product
    Discover our top product ADAM32 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ADAM32 (ADAM Metallopeptidase Domain 32 (ADAM32))
    Andere Bezeichnung
    ADAM32 (ADAM32 Produkte)
    Synonyme
    ADAM metallopeptidase domain 32 antikoerper, disintegrin and metalloproteinase domain-containing protein 32 antikoerper, a disintegrin and metallopeptidase domain 32 antikoerper, ADAM32 antikoerper, LOC100525542 antikoerper, Adam32 antikoerper
    Hintergrund

    Synonyms: A disintegrin and metalloproteinase domain 32, ADA32_HUMAN, ADAM 32, Adam32, Disintegrin and metalloproteinase domain-containing protein 32.

    Background: ADAM32 was first discovered in a search for testis-specific proteinases. ADAM32 was identified in human, rat, mouse, macaque and chimp, and thus far has been found only in testis. In mice, ADAM32 is found on the sperm surface, where it may play a role in fertilization. ADAM32 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full length ADAM32 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a short spacer region, then the transmembrane domain and a cytoplasmic domain. Like many of the reproductive-specific ADAMS, ADAM32 plays a non-enzymatic role, or (as is the case for ADAMs 1 & 2 (fertilin alpha and beta)), the protein acts in concert with a proteolytically active ADAM to process proteins. Little is known about interactions between ADAM32 and other ADAMs. Several different sequences for human ADAM32 are published, 787, 688, 649, 629, and 279 amino acids in length. The 688 amino acid form is identical to the 787 AA form until the EGF-like domain, and lacks the TM and cytoplasmic domains. The 649 AA form is likewise identical to the longer form, just to the start of the TM domain, and also lacks the TM and cytoplasmic domains. The 629 AA form has a deletion of 107 residues midway into the MP-like domain, and lacks the amino end of the disintegrin domain, but contains the rest of the domains found in the full-length ADAM32. The predicted masses for the different versions are 87.8, 76.9, 72.9, 70.9 and 32.1, respectively, for the 786, 688, 649, 629 and 279 AA forms.

    Gen-ID
    203102
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