PAEP Antikörper

Produktnummer ABIN8065527

Der Maus Monoklonal anti-PAEP Antikörper wird verwendet zum Nachweis von PAEP in Proben von Human. Er wurde validiert für ELISA und IHC.

Kurzübersicht für PAEP Antikörper (ABIN8065527)

Target: PAEP (Progestagen-Associated Endometrial Protein (PAEP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAEP Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Klon: 16

Produktdetails anti-PAEP Antikörper

Verwendungszweck: Anti-Placental Protein 14 Antibody

Spezifität: BTE 001-16 is specific for human PP14 protein 14 (human, PP14, glycodelin A). Epitode differs from BTE 001-13

Homologie: Human

Aufreinigung: Protein A or Protein G purified

Immunogen: Placental protein 14 (glycodelin A) purified from second trimester amniotic fluid

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C without exposure to light

Haltbarkeit: 24 months

Details zu PAEP

Target: PAEP (Progestagen-Associated Endometrial Protein (PAEP))

Andere Bezeichnung: Placental Protein 14

Hintergrund: PAEP, GD, GdA, GdF, GdS, PAEG, PEP, PP14, ZIF-1, glycodelin, PEG, PP14 protein (placental protein 14), alpha uterine protein, glycodelin-A, glycodelin-F, glycodelin-S, placental protein 14, pregnancy-associated endometrial alpha-2 globulin, progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial a, progesterone-associated endometrial protein, zona-binding inhibitory factor-1,Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:7531163, PubMed:9918684). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155). {ECO:0000269|PubMed:12672671, ECO:0000269|PubMed:15883155, ECO:0000269|PubMed:17192260, ECO:0000269|PubMed:7531163, ECO:0000269|PubMed:9918684}.,PAEP,Human placental protein 14 (PP14, also known as glycodelin and progesterone-associated endometrial protein) is a protein of the lipocalin structural superfamily. PP14 is the most abundant product of the secretory endometrium, and has been proposed as a biochemical marker of endometrial function in women undergoing in vitro fertilization treatment. (1)

Molekulargewicht: 20 kDa

Gen-ID: 5047

UniProt: P09466