Peptide YY Antikörper (N-Term)
Kurzübersicht für Peptide YY Antikörper (N-Term) (ABIN8065519)
Target
Alle Peptide YY (PYY) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- N-Term
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Verwendungszweck
- Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody
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Spezifität
- ABIN8065519 binds human PYY(3-36). Based on inhibition ELISA, ABIN8065519 shows no cross-reaction with PYY(1-36) or NPY. The epitope lies within residues 3-12 of human PYY.
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Homologie
- Human
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Aufreinigung
- Protein A or Protein G purified
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Immunogen
- Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C without exposure to light
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Haltbarkeit
- 24 months
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- Peptide YY (PYY)
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Andere Bezeichnung
- PYY
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Hintergrund
- PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY,This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.,PYY,Peptide tyrosine-tyrosine amide (3-36), or PYY(3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY(3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY(3-36) is additive to that of the co-secreted gut hormone GLP-1.
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Molekulargewicht
- 4 kDa
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Gen-ID
- 5697
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UniProt
- P10082
Target
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