PPY Antikörper
Kurzübersicht für PPY Antikörper (ABIN8065515)
Target
Alle PPY Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- Anti-Pancreatic Polypeptide Antibody
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Spezifität
- ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1 % .
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Homologie
- Human
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Aufreinigung
- Protein A or Protein G purified
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Immunogen
- Synthetic human PP
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C without exposure to light
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Haltbarkeit
- 24 months
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- PPY (Pancreatic Polypeptide (PPY))
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Andere Bezeichnung
- Pancreatic Polypeptide
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Hintergrund
- PPY, PH, PNP, PP, pancreatic polypeptide prohormone, pancreatic polypeptide Y, pancreatic prohormone, prepro-PP (prepropancreatic polypeptide),[Pancreatic polypeptide]: Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2. {ECO:0000269|PubMed:7493937, ECO:0000269|PubMed:7592911}.,PPY,Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.
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Molekulargewicht
- 10 kDa
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Gen-ID
- 5539
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UniProt
- P01298
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Pathways
- Feeding Behaviour
Target
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