Exendin 4 Antikörper

Produktnummer ABIN8065458

Der Maus Monoklonal anti-Exendin 4 Antikörper wird verwendet zum Nachweis von Exendin 4 in Proben von Gila monster. Er wurde validiert für ELISA.

Kurzübersicht für Exendin 4 Antikörper (ABIN8065458)

Target: Exendin 4

Reaktivität: Gila monster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Exendin 4 Antikörper ist unkonjugiert

Applikation: ELISA

Güteklasse: Carrier-free

Klon: 35

Produktdetails anti-Exendin 4 Antikörper

Verwendungszweck: Anti-Exendin-4 Antibody

Spezifität: Specific for exendin-4. No cross-reactivity with GLP-1, GLP-2 (human) or glucagon coated on ELISA wells. The epitope is in the 9-39 region of the peptide, and the antibody cross-reacts strongly with exendin (9-39) amide.

Homologie: Gila monster Heloderma suspectum

Aufreinigung: Protein A or Protein G purified

Immunogen: Synthetic exendin-4

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C without exposure to light

Haltbarkeit: 12 months

Details zu Exendin 4

Target: Exendin 4

Andere Bezeichnung: Exendin-4

Hintergrund: Exenatide,Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.,N/A,Exendin-4 is a 39 amino acid peptide found in venom from the Gila monster Heloderma suspectum. It is a member of the glucagon-secretin family of peptide hormones and neuropeptides. Exendin-4 is a potent agonist of the GLP-1 receptor and hence a potent stimulator of insulin secretion.

Molekulargewicht: 4.2 kDa

UniProt: P26349