ZEB2 Antikörper (AA 1-200) (Fluoro647)

Produktnummer ABIN8055205

Der Fluoro647-konjugierte Kaninchen Polyklonal anti-ZEB2 Antikörper (ABIN8055205) detektiert spezifisch ZEB2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ZEB2 Antikörper (AA 1-200) (Fluoro647) (ABIN8055205)

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZEB2 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ZEB2 Antikörper (Fluoro647)

Bindungsspezifität: AA 1-200

Verwendungszweck: Anti-Smad Interacting Protein 1/ZEB2 Antibody Fluoro647 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ZEB2 recombinant protein (Position: M1-P200). Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Andere Bezeichnung: ZEB2

Hintergrund:

Background: ZEB2 (Zinc finger E-box-binding homeobox2), also known as SIP1 or ZINC FINGER HOMEOBOX 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 gene is a member of the ZEB1/Drosophila Zfh1 family of 2-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs, the transducers of TGF-beta signaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated following SNAI1 expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.

Gene Full Name: zinc finger E-box binding homeobox 2

Sequence Similarities: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

Gen-ID: 9839

UniProt: O60315

Pathways: Tube Formation