WWOX Antikörper (AA 1-245) (HRP)

Produktnummer ABIN8054552

Dieser Maus Monoklonal Antikörper detektiert spezifisch WWOX in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für WWOX Antikörper (AA 1-245) (HRP) (ABIN8054552)

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WWOX Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 3D10

Produktdetails anti-WWOX Antikörper (HRP)

Bindungsspezifität: AA 1-245

Verwendungszweck: Anti-WWOX Antibody (monoclonal, 3D10) HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human WWOX recombinant protein (Position: M1-D245).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu WWOX

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Andere Bezeichnung: WWOX

Hintergrund:

Background: WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. It spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Gene Full Name: WW domain containing oxidoreductase

Gen-ID: 51741

UniProt: Q9NZC7