VAV3 Antikörper (AA 507-702) (HRP)

Produktnummer ABIN8053550

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VAV3 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für VAV3 Antikörper (AA 507-702) (HRP) (ABIN8053550)

Target: VAV3 (Vav 3 Oncogene (VAV3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAV3 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-VAV3 Antikörper (HRP)

Bindungsspezifität: AA 507-702

Verwendungszweck: Anti-VAV3 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human VAV3 recombinant protein (Position: D507-E702).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Andere Bezeichnung: VAV3

Hintergrund:

Background: Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene. This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: vav guanine nucleotide exchange factor 3

Gen-ID: 10451

UniProt: Q9UKW4

Pathways: Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung