ULBP1 Antikörper (AA 27-209) (Fluoro647)

Produktnummer ABIN8052739

Der Fluoro647-konjugierte Kaninchen Polyklonal anti-ULBP1 Antikörper (ABIN8052739) detektiert spezifisch ULBP1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ULBP1 Antikörper (AA 27-209) (Fluoro647) (ABIN8052739)

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULBP1 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ULBP1 Antikörper (Fluoro647)

Bindungsspezifität: AA 27-209

Verwendungszweck: Anti-ULBP1 Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ULBP1 recombinant protein (Position: W27-K209).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ULBP1

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Andere Bezeichnung: ULBP1

Hintergrund:

Background: UL16 binding protein 1 (ULBP1) is a cell surface glycoprotein encoded by ULBP1 gene located on the chromosome 6. The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: UL16 binding protein 1

Gen-ID: 80329

UniProt: Q9BZM6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process