UGT1A1 Antikörper (AA 57-248) (Biotin)

Produktnummer ABIN8052586

Der Biotin-konjugierte Kaninchen Polyklonal anti-UGT1A1 Antikörper (ABIN8052586) detektiert spezifisch UGT1A1 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.

Kurzübersicht für UGT1A1 Antikörper (AA 57-248) (Biotin) (ABIN8052586)

Target: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-UGT1A1 Antikörper (Biotin)

Bindungsspezifität: AA 57-248

Verwendungszweck: Anti-Ugt1a1 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Ugt1a1 recombinant protein (Position: H57-D248).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu UGT1A1

Target: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Andere Bezeichnung: Ugt1a1

Hintergrund:

Background: UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene. Predicted to enable several functions, including glucuronosyltransferase activity, protein dimerization activity, and retinoic acid binding activity. Predicted to be involved in several processes, including biphenyl catabolic process, cellular glucuronidation, and negative regulation of cellular glucuronidation. Is integral component of plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in alimentary system, nervous system, and urinary system. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple), cholecystolithiasis, cholelithiasis, female reproductive organ cancer (multiple), and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1).

Gene Full Name: UDP glucuronosyltransferase 1 family, polypeptide A1

Gen-ID: 394436

UniProt: Q63886

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha