TNK2 Antikörper (AA 491-1038) (APC)
Kurzübersicht für TNK2 Antikörper (AA 491-1038) (APC) (ABIN8051816)
Target
Alle TNK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 491-1038
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Verwendungszweck
- Anti-ACK1/TNK2 Antibody APC Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human TNK2/ACK1 recombinant protein (Position: M491-R1038).
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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Andere Bezeichnung
- TNK2
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Hintergrund
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Background: Activated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the TNK2 gene. This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is ly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Gene Full Name: tyrosine kinase non receptor 2
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Gen-ID
- 10188
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UniProt
- Q07912
Target
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