CREM Antikörper (AA 251-361)

Produktnummer ABIN755362

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CREM in ELISA, IF (cc), IF (p), FACS, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CREM Antikörper (AA 251-361) (ABIN755362)

Target: CREM (CAMP Responsive Element Modulator (CREM))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREM Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CREM Antikörper

Bindungsspezifität: AA 251-361

Kreuzreaktivität: Human, Maus

Homologie: Rat,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CREM

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Andere Bezeichnung: CREM

Hintergrund:

Synonyms: cAMP response element modulator, CREM-1, cAMP responsive element modulator, hCREM 2, hCREM2, ICER, Inducible cAMP early repressor, Inducible cAMP early repressor ICER, MGC111110, MGC17881, MGC41893.

Background: CREM is a a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is derived from a multiexonic gene that encodes both activators and antagonists of cAMP-inducible transcription by differential splicing. Splice variants with antagonistic function lack 2 glutamine-rich domains and block cAMP-induced transcription, whereas an isoform that includes these glutamine-rich domains is a transcriptional activator.

Gen-ID: 1390

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway