TMC6 Antikörper (AA 1-772) (Fluoro550)

Produktnummer ABIN8048880

Der Kaninchen Polyklonal anti-TMC6 Antikörper wird verwendet zum Nachweis von TMC6 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für TMC6 Antikörper (AA 1-772) (Fluoro550) (ABIN8048880)

Target: TMC6 (Transmembrane Channel-Like 6 (TMC6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMC6 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-TMC6 Antikörper (Fluoro550)

Bindungsspezifität: AA 1-772

Verwendungszweck: Anti-TMC6 Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human TMC6 shares 76.7% amino acid (aa) sequence identity with mouse TMC6.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TMC6 recombinant protein (Position: M1-H772). Human TMC6 shares 76.7% amino acid (aa) sequence identity with mouse TMC6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu TMC6

Target: TMC6 (Transmembrane Channel-Like 6 (TMC6))

Andere Bezeichnung: TMC6

Hintergrund:

Background: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.

Gene Full Name: transmembrane channel like 6

Gen-ID: 11322

UniProt: Q7Z403