SOX9 Antikörper (AA 121-220)

Produktnummer ABIN754963

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SOX9 in WB, ELISA, FACS, IHC (p), IF (p), IF (cc) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Kaninchen und wurde in 9+ Publikationen erwähnt.

Kurzübersicht für SOX9 Antikörper (AA 121-220) (ABIN754963)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reaktivität: Human, Maus, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-SOX9 Antikörper

Bindungsspezifität: AA 121-220

Kreuzreaktivität: Human, Maus, Kaninchen, Ratte

Homologie: Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOX9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SOX9 Antikörper (ABIN754963)

Webster, Cooley-Themm, Barnett, Bach, Vainner, Webster, Linn: "Evidence of BrdU-positive retinal neurons after application of an Alpha7 nicotinic acetylcholine receptor agonist." in: Neuroscience, Vol. 346, pp. 437-446, (2017) (PubMed).

Montorsi, Guizzetti, Alecci, Caporali, Martello, Atene, Parenti, Pizzini, Zanovello, Bortoluzzi, Ferrari, Grande, Zanocco-Marani: "Loss of zfp36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." in: Oncotarget, Vol. 7, Issue 37, pp. 59144-59157, (2016) (PubMed).

Yang, Lu, Guo: "Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis." in: Molecular medicine reports, Vol. 14, Issue 5, pp. 4075-4082, (2016) (PubMed).

Chang, Lin, Lin, Wang, Hsu, Yeh: "The repair of full-thickness articular cartilage defect using intra-articular administration of N-acetyl-D-glucosamine in the rabbit knee: randomized controlled trial." in: Biomedical engineering online, Vol. 14, pp. 105, (2016) (PubMed).

Wu, Zhu, Sun, Hu: "Subchondral bone changes and chondrogenic capacity of progenitor cells from subchondral bone in the collagenase-induced temporomandibular joints osteoarthritis rabbit model." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 9782-9, (2016) (PubMed).

Wang, Ju, Sun, Hou, Yang, Zhang: "Overexpression of heparan sulfate 6-O-sulfotransferase-2 enhances fibroblast growth factor-mediated chondrocyte growth and differentiation." in: International journal of molecular medicine, Vol. 36, Issue 3, pp. 825-32, (2015) (PubMed).

Papaioannou, Mirzamohammadi, Lisse, Nishimori, Wein, Kobayashi: "MicroRNA-140 provides robustness to the regulation of hypertrophic chondrocyte differentiation by the PTHrP-HDAC4 pathway." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2014) (PubMed).

Mi, Chen, Wu, Wang, Gao: "Study of the effect of miR‑124 and the SOX9 target gene in Hirschsprung's disease." in: Molecular medicine reports, Vol. 9, Issue 5, pp. 1839-43, (2014) (PubMed).

Details zu SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Andere Bezeichnung: SOX9

Hintergrund:

Synonyms: CMD1, SRA1, CMPD1, Transcription factor SOX-9, SOX9

Background: Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

Gen-ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development