SYCP3 Antikörper (AA 18-223) (Fluoro488)

Produktnummer ABIN8044342

Der Fluoro488-konjugierte Kaninchen Polyklonal anti-SYCP3 Antikörper (ABIN8044342) detektiert spezifisch SYCP3 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SYCP3 Antikörper (AA 18-223) (Fluoro488) (ABIN8044342)

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYCP3 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SYCP3 Antikörper (Fluoro488)

Bindungsspezifität: AA 18-223

Verwendungszweck: Anti-SCP3/SYCP3 Antibody Fluoro488 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SCP3 shares 72%,73% amino acid (aa) sequences identity with mouse,rat SCP3,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SCP3 recombinant protein (Position: E18-E223). Human SCP3 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat SCP3, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SYCP3

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Andere Bezeichnung: SYCP3

Hintergrund:

Background: SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.

Gene Full Name: synaptonemal complex protein 3

Gen-ID: 50511

UniProt: Q8IZU3