SYN2 Antikörper (AA 497-582) (Biotin)

Produktnummer ABIN8044241

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SYN2 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus, Human, Ratte und Schwein.

Kurzübersicht für SYN2 Antikörper (AA 497-582) (Biotin) (ABIN8044241)

Target: SYN2 (Synapsin II (SYN2))

Reaktivität: Maus, Human, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYN2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-SYN2 Antikörper (Biotin)

Bindungsspezifität: AA 497-582

Verwendungszweck: Anti-Synapsin II/SYN2 Antibody Biotin Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1%,89.7% amino acid (aa) sequence identity with mouse,rat Synapsin II,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1% and 89.7% amino acid (aa) sequence identity with mouse and rat Synapsin II, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SYN2

Target: SYN2 (Synapsin II (SYN2))

Andere Bezeichnung: SYN2

Hintergrund:

Background: Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite ion.

Gene Full Name: synapsin II

Gen-ID: 6854

UniProt: Q92777