STRIP2 Antikörper (AA 173-507) (Fluoro488)

Produktnummer ABIN8043030

Der Kaninchen Polyklonal anti-STRIP2 Antikörper wird verwendet zum Nachweis von STRIP2 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für STRIP2 Antikörper (AA 173-507) (Fluoro488) (ABIN8043030)

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRIP2 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-STRIP2 Antikörper (Fluoro488)

Bindungsspezifität: AA 173-507

Verwendungszweck: Anti-FAM40B/STRIP2 Antibody Fluoro488 Conjugated

Homologie: Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FAM40B/STRIP2 recombinant protein (Position: H173-Q507). Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu STRIP2

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Andere Bezeichnung: STRIP2

Hintergrund:

Background: The STRIP2 gene encodes a protein known as striatin-interacting protein 2, which interacts with striatin, a scaffolding protein involved in diverse cellular processes such as signaling, cell adhesion, and transcriptional regulation. STRIP2 is implicated in cardiac development and function, where it modulates cardiac hypertrophy, contractility, and arrhythmogenesis. Additionally, it plays roles in neuronal development and synaptic plasticity in the brain. Dysregulation of STRIP2 expression or function has been associated with various cardiovascular disorders, including hypertrophic cardiomyopathy and arrhythmias, as well as neurodevelopmental disorders such as autism spectrum disorders. Elucidating the molecular mechanisms underlying STRIP2 function is essential for understanding its physiological roles in cardiac and neural tissues and its potential implications for disease pathology and therapeutic targeting.

Gene Full Name: striatin interacting protein 2

Gen-ID: 57464

UniProt: Q9ULQ0