SRA1 Antikörper (AA 1-224) (HRP)

Produktnummer ABIN8042769

Der Kaninchen Polyklonal anti-SRA1 Antikörper wird verwendet zum Nachweis von SRA1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für SRA1 Antikörper (AA 1-224) (HRP) (ABIN8042769)

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRA1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SRA1 Antikörper (HRP)

Bindungsspezifität: AA 1-224

Verwendungszweck: Anti-SRA1 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SRA1 shares 81.8%,80% amino acid (aa) sequence identity with mouse,rat SRA1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SRA1 recombinant protein (Position: M1-S224). Human SRA1 shares 81.8% and 80% amino acid (aa) sequence identity with mouse and rat SRA1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Andere Bezeichnung: SRA1

Hintergrund:

Background: Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA.

Gene Full Name: steroid receptor RNA activator 1

Gen-ID: 10011

UniProt: Q9HD15

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development