PLCL1 Antikörper (AA 1001-1096) (HRP)

Produktnummer ABIN754597

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PLCL1 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für PLCL1 Antikörper (AA 1001-1096) (HRP) (ABIN754597)

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLCL1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PLCL1 Antikörper (HRP)

Bindungsspezifität: AA 1001-1096

Spezifität: This antibody may exhibit a slight secondary cross-reactivity with PLCL2 due to a 69 % non-sequential sequence similarity over the immunogen range.

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLCL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PLCL1

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Andere Bezeichnung: PLCL1

Hintergrund:

Synonyms: PLCL1, PLCE, Phospholipase C deleted in lung carcinoma, Phospholipase C epsilon, Phospholipase C like 1, Phospholipase C related but catalytically inactive protein, Phospholipase C related, but catalytically inactive protein, PLCE, PLCL, PRIP, Plcl1, C230017K02Rik, KIAA1092, PLC-L, PLC-L1, PLCE, PLCL, PRIP, PRIP-1, PLCL1_HUMAN.

Background: PLCL1 is involved an inositol phospholipid based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.

Gen-ID: 5334