STRADB Antikörper (AA 24-411) (Fluoro647)

Produktnummer ABIN8042682

Der Kaninchen Polyklonal anti-STRADB Antikörper wird verwendet zum Nachweis von STRADB in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für STRADB Antikörper (AA 24-411) (Fluoro647) (ABIN8042682)

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADB Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-STRADB Antikörper (Fluoro647)

Bindungsspezifität: AA 24-411

Verwendungszweck: Anti-STRADB Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human STRADB recombinant protein (Position: E24-E411).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Andere Bezeichnung: STRADB

Hintergrund:

Background: STE20-related kinase adapter protein beta is an enzyme that in humans is encoded by the STRADB gene. This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: STE20 related adaptor beta

Gen-ID: 55437

UniProt: Q9C0K7

Pathways: AMPK Signaling