Stanniocalcin 2 Antikörper (AA 51-226) (APC)

Produktnummer ABIN8042525

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Stanniocalcin 2 in WB, IHC, ICC, ELISA, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Stanniocalcin 2 Antikörper (AA 51-226) (APC) (ABIN8042525)

Target: Stanniocalcin 2 (STC2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Stanniocalcin 2 Antikörper ist konjugiert mit APC

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Stanniocalcin 2 Antikörper (APC)

Bindungsspezifität: AA 51-226

Verwendungszweck: Anti-Stanniocalcin 2/STC2 Antibody APC Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human STC2 shares 90.3%,89.8% amino acid (aa) sequence identity with mouse,rat STC2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Stanniocalcin 2/STC2 recombinant protein (Position: A51-Q226). Human STC2 shares 90.3% and 89.8% amino acid (aa) sequence identity with mouse and rat STC2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Kommentare:

Applications are recommended based on the unconjugated antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Stanniocalcin 2

Target: Stanniocalcin 2 (STC2)

Andere Bezeichnung: STC2

Hintergrund:

Background: Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Gene Full Name: stanniocalcin 2

Gen-ID: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interaktom