Stanniocalcin 2 Antikörper (AA 51-226) (HRP)

Produktnummer ABIN8042524

Der HRP-konjugierte Kaninchen Polyklonal anti-Stanniocalcin 2 Antikörper (ABIN8042524) detektiert spezifisch Stanniocalcin 2 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Stanniocalcin 2 Antikörper (AA 51-226) (HRP) (ABIN8042524)

Target: Stanniocalcin 2 (STC2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Stanniocalcin 2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Stanniocalcin 2 Antikörper (HRP)

Bindungsspezifität: AA 51-226

Verwendungszweck: Anti-Stanniocalcin 2/STC2 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human STC2 shares 90.3%,89.8% amino acid (aa) sequence identity with mouse,rat STC2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Stanniocalcin 2/STC2 recombinant protein (Position: A51-Q226). Human STC2 shares 90.3% and 89.8% amino acid (aa) sequence identity with mouse and rat STC2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Stanniocalcin 2

Target: Stanniocalcin 2 (STC2)

Andere Bezeichnung: STC2

Hintergrund:

Background: Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Gene Full Name: stanniocalcin 2

Gen-ID: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interaktom