SOX7 Antikörper (C-Term) (Cy3)

Produktnummer ABIN8042373

Der Kaninchen Polyklonal anti-SOX7 Antikörper wird verwendet zum Nachweis von SOX7 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für SOX7 Antikörper (C-Term) (Cy3) (ABIN8042373)

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX7 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SOX7 Antikörper (Cy3)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-SOX7 Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SOX7, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Andere Bezeichnung: SOX7

Hintergrund:

Background: SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In cotransfected 293 cells, Sox7 reduced Wnt (see WNT1)/beta-catenin (see CTNNB1)- stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.

Gene Full Name: SRY-box transcription factor 7

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Gen-ID: 83595

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity