SPATA18 Antikörper (AA 27-490) (Cy3)
Kurzübersicht für SPATA18 Antikörper (AA 27-490) (Cy3) (ABIN8041542)
Target
Alle SPATA18 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 27-490
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Verwendungszweck
- Anti-SPATA18 Antibody Cy3 Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human SPATA18 recombinant protein (Position: E27-R490).
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, 1-3 μg/1x106 cells
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- SPATA18 (Spermatogenesis Associated 18 (SPATA18))
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Andere Bezeichnung
- SPATA18
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Hintergrund
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Background: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.
Gene Full Name: spermatogenesis associated 18
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Gen-ID
- 132671
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UniProt
- Q8TC71
Target
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