SPA17 Antikörper (AA 1-136)
Kurzübersicht für SPA17 Antikörper (AA 1-136) (ABIN8041484)
Target
Alle SPA17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 1-136
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Verwendungszweck
- Anti-SPA17 Antibody
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Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
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Homologie
- Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.
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Produktmerkmale
- Anti-SPA17 Antibody. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human SPA17 recombinant protein (Position: M1-K136). Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Haltbarkeit
- 12 months
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- SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
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Andere Bezeichnung
- SPA17
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Hintergrund
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Background: Sperm surface protein Sp17 is a protein that in humans is encoded by the SPA17 gene. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
Gene Full Name: sperm autoantigenic protein 17
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Molekulargewicht
- 22 kDa
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Gen-ID
- 53340
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UniProt
- Q15506
Target
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