SPA17 Antikörper (AA 1-136) (Cy3)

Produktnummer ABIN8041475

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPA17 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für SPA17 Antikörper (AA 1-136) (Cy3) (ABIN8041475)

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPA17 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SPA17 Antikörper (Cy3)

Bindungsspezifität: AA 1-136

Verwendungszweck: Anti-SPA17 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SPA17 recombinant protein (Position: M1-K136). Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Andere Bezeichnung: SPA17

Hintergrund:

Background: Sperm surface protein Sp17 is a protein that in humans is encoded by the SPA17 gene. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Gene Full Name: sperm autoantigenic protein 17

Gen-ID: 53340

UniProt: Q15506