SNX15 Antikörper (AA 8-327) (Fluoro488)

Produktnummer ABIN8040922

Der Fluoro488-konjugierte Kaninchen Polyklonal anti-SNX15 Antikörper (ABIN8040922) detektiert spezifisch SNX15 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SNX15 Antikörper (AA 8-327) (Fluoro488) (ABIN8040922)

Target: SNX15 (Sorting Nexin 15 (SNX15))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX15 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SNX15 Antikörper (Fluoro488)

Bindungsspezifität: AA 8-327

Verwendungszweck: Anti-SNX15 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SNX15 recombinant protein (Position: D8-K327).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Andere Bezeichnung: SNX15

Hintergrund:

Background: Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Gene Full Name: sorting nexin 15

Gen-ID: 29907

UniProt: Q9NRS6