SORD Antikörper (AA 8-357)

Produktnummer ABIN8040864

Der Maus Monoklonal anti-SORD Antikörper wird verwendet zum Nachweis von SORD in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC und FACS.

Kurzübersicht für SORD Antikörper (AA 8-357) (ABIN8040864)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SORD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: 12B10G2

Produktdetails anti-SORD Antikörper

Bindungsspezifität: AA 8-357

Verwendungszweck: Anti-Sorbitol Dehydrogenase/SORD Antibody (monoclonal, 12B10G2)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Sorbitol Dehydrogenase/SORD Antibody.(monoclonal, 12B10G2)-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Andere Bezeichnung: SORD

Hintergrund:

Background: Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene. Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Gene Full Name: sorbitol dehydrogenase

Molekulargewicht: 40 kDa

Gen-ID: 6652

UniProt: Q00796