SNAIL Antikörper (AA 1-170) (Cy3)

Produktnummer ABIN8038568

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SNAIL in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SNAIL Antikörper (AA 1-170) (Cy3) (ABIN8038568)

Target: SNAIL (SNAI1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAIL Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SNAIL Antikörper (Cy3)

Bindungsspezifität: AA 1-170

Verwendungszweck: Anti-SNAIL/SNAI1 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SNAIL/SNAI1 recombinant protein (Position: M1-K170).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: SNAI1

Hintergrund:

Background: The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.

Gene Full Name: snail family transcriptional repressor 1

Gen-ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling