SIVA1 Antikörper (AA 1-141) (Biotin)

Produktnummer ABIN8037860

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SIVA1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SIVA1 Antikörper (AA 1-141) (Biotin) (ABIN8037860)

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIVA1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SIVA1 Antikörper (Biotin)

Bindungsspezifität: AA 1-141

Verwendungszweck: Anti-SIVA/SIVA1 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SIVA/SIVA1 recombinant protein (Position: M1-T141).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SIVA1

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Andere Bezeichnung: SIVA1

Hintergrund:

Background: Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene. This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.

Gene Full Name: SIVA1 apoptosis inducing factor

Gen-ID: 10572

UniProt: O15304

Pathways: Positive Regulation of Endopeptidase Activity