SIRT6 Antikörper (AA 14-355) (HRP)
Kurzübersicht für SIRT6 Antikörper (AA 14-355) (HRP) (ABIN8037844)
Target
Alle SIRT6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 14-355
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Verwendungszweck
- Anti-SIRT6 Antibody HRP Conjugated
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Homologie
- Human SIRT6 shares 82.7% amino acid (aa) sequence identity with both mouse SIRT6.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human SIRT6 recombinant protein (Position: D14-S355). Human SIRT6 shares 82.7% amino acid (aa) sequence identity with both mouse SIRT6.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- SIRT6 (Sirtuin 6 (SIRT6))
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Andere Bezeichnung
- SIRT6
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Hintergrund
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Background: Sirtuin 6 (SIRT6 or Sirt6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene. This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: sirtuin 6
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Gen-ID
- 51548
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UniProt
- Q8N6T7
Target
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