SIM2 Antikörper (AA 337-609) (HRP)

Produktnummer ABIN8037734

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SIM2 in ELISA, WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Affe.

Kurzübersicht für SIM2 Antikörper (AA 337-609) (HRP) (ABIN8037734)

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIM2 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SIM2 Antikörper (HRP)

Bindungsspezifität: AA 337-609

Verwendungszweck: Anti-SIM2 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SIM2 recombinant protein (Position: Y337-R609). Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SIM2

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Andere Bezeichnung: SIM2

Hintergrund:

Background: Single-minded homolog 2 is a protein that in humans is encoded by the SIM2 gene. This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: SIM bHLH transcription factor 2

Gen-ID: 6493

UniProt: Q14190