SH3BP2 Antikörper (AA 256-561) (APC)

Produktnummer ABIN8036951

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SH3BP2 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SH3BP2 Antikörper (AA 256-561) (APC) (ABIN8036951)

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3BP2 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SH3BP2 Antikörper (APC)

Bindungsspezifität: AA 256-561

Verwendungszweck: Anti-3BP2/SH3BP2 Antibody APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human 3BP2/SH3BP2 recombinant protein (Position: R256-R561).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SH3BP2

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Andere Bezeichnung: SH3BP2

Hintergrund:

Background: SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: SH3 domain binding protein 2

Gen-ID: 6452

UniProt: P78314

Pathways: T-Zell Rezeptor Signalweg