STK4 Antikörper (AA 324-452) (PE)

Produktnummer ABIN8036134

Der PE-konjugierte Kaninchen Polyklonal anti-STK4 Antikörper (ABIN8036134) detektiert spezifisch STK4 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für STK4 Antikörper (AA 324-452) (PE) (ABIN8036134)

Target: STK4 (serine/threonine Kinase 4 (STK4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-STK4 Antikörper (PE)

Bindungsspezifität: AA 324-452

Verwendungszweck: Anti-MST1/STK4 Antibody PE Conjugated

Homologie: Human STK4 shares 93.8% amino acid (aa) sequence identity with mouse STK4.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MST1/STK4 recombinant protein (Position: E324-D452). Human STK4 shares 93.8% amino acid (aa) sequence identity with mouse STK4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Andere Bezeichnung: MST1/STK4

Hintergrund:

Background: Serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the STK4 gene. The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Gene Full Name: serine/threonine kinase 4

Gen-ID: 6789

UniProt: Q13043

Pathways: Tube Formation