Septin 5 Antikörper (C-Term)

Produktnummer ABIN8035725

Der Kaninchen Polyklonal anti-Septin 5 Antikörper wird verwendet zum Nachweis von Septin 5 in Proben von Human und Ratte. Er wurde validiert für WB und FACS.

Kurzübersicht für Septin 5 Antikörper (C-Term) (ABIN8035725)

Target: Septin 5 (SEPT5)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-Septin 5 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-SEPT5/SEPTIN5 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Produktmerkmale: Anti-SEPT5/SEPTIN5 Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SEPT5/SEPTIN5, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL/mL, Human Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human, Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: SEPTIN5

Hintergrund:

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Gene Full Name: septin 5

Molekulargewicht: 42 kDa

Gen-ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis