Septin 5 Antikörper (C-Term) (Fluoro647)

Produktnummer ABIN8035724

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Septin 5 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Septin 5 Antikörper (C-Term) (Fluoro647) (ABIN8035724)

Target: Septin 5 (SEPT5)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Septin 5 Antikörper (Fluoro647)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-SEPT5/SEPTIN5 Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SEPT5/SEPTIN5, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: SEPTIN5

Hintergrund:

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Gene Full Name: septin 5

Gen-ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis