Senataxin (SETX) (AA 28-2447) Antikörper

Produktnummer ABIN8035637

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Senataxin in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für Senataxin (SETX) (AA 28-2447) Antikörper (ABIN8035637)

Target: Senataxin (SETX)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Produktdetails

Bindungsspezifität: AA 28-2447

Verwendungszweck: Anti-SETX Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Produktmerkmale: Anti-SETX Antibody. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse SETX recombinant protein (Position: S28-R2447). Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Senataxin (SETX)

Andere Bezeichnung: SETX

Hintergrund:

Background: Predicted to enable RNA binding activity, identical protein binding activity, and transcription termination site sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and termination of RNA polymerase II transcription. Predicted to be located in several cellular components, including growth cone, intercellular bridge, and nuclear lumen. Predicted to be active in nuclear body. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study amyotrophic lateral sclerosis type 4. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4 and spinocerebellar ataxia with axonal neuropathy 2. Orthologous to human SETX (senataxin).

Gene Full Name: senataxin

Molekulargewicht: 303 kDa

Gen-ID: 269254

UniProt: A2AKX3