Senataxin (SETX) (AA 28-2447) Antikörper (APC)

Produktnummer ABIN8035634

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Senataxin in FACS. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für Senataxin (SETX) (AA 28-2447) Antikörper (APC) (ABIN8035634)

Target: Senataxin (SETX)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: APC

Applikation: Flow Cytometry (FACS)

Produktdetails

Bindungsspezifität: AA 28-2447

Verwendungszweck: Anti-SETX Antibody APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse SETX recombinant protein (Position: S28-R2447). Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Antigendetails

Target: Senataxin (SETX)

Andere Bezeichnung: SETX

Hintergrund:

Background: Predicted to enable RNA binding activity, identical protein binding activity, and transcription termination site sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and termination of RNA polymerase II transcription. Predicted to be located in several cellular components, including growth cone, intercellular bridge, and nuclear lumen. Predicted to be active in nuclear body. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study amyotrophic lateral sclerosis type 4. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4 and spinocerebellar ataxia with axonal neuropathy 2. Orthologous to human SETX (senataxin).

Gene Full Name: senataxin

Gen-ID: 269254

UniProt: A2AKX3