SECISBP2 Antikörper (AA 12-854)

Produktnummer ABIN8035053

Der Kaninchen Polyklonal anti-SECISBP2 Antikörper wird verwendet zum Nachweis von SECISBP2 in Proben von Human. Er wurde validiert für WB, ELISA, IF und ICC.

Kurzübersicht für SECISBP2 Antikörper (AA 12-854) (ABIN8035053)

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SECISBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Güteklasse: Carrier-free

Produktdetails anti-SECISBP2 Antikörper

Bindungsspezifität: AA 12-854

Verwendungszweck: Anti-SECISBP2 Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Produktmerkmale: Anti-SECISBP2 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SECISBP2

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Andere Bezeichnung: SECISBP2

Hintergrund:

Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: SECIS binding protein 2

Molekulargewicht: 105 kDa

Gen-ID: 79048

UniProt: Q96T21