SECISBP2 Antikörper (AA 12-854) (FITC)

Produktnummer ABIN8035048

Der FITC-konjugierte Kaninchen Polyklonal anti-SECISBP2 Antikörper (ABIN8035048) detektiert spezifisch SECISBP2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SECISBP2 Antikörper (AA 12-854) (FITC) (ABIN8035048)

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SECISBP2 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SECISBP2 Antikörper (FITC)

Bindungsspezifität: AA 12-854

Verwendungszweck: Anti-SECISBP2 Antibody FITC Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SECISBP2

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Andere Bezeichnung: SECISBP2

Hintergrund:

Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: SECIS binding protein 2

Gen-ID: 79048

UniProt: Q96T21