SEC63 Antikörper (AA 37-760) (Fluoro550)

Produktnummer ABIN8035013

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SEC63 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SEC63 Antikörper (AA 37-760) (Fluoro550) (ABIN8035013)

Target: SEC63 (SEC63 Homolog (SEC63))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC63 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SEC63 Antikörper (Fluoro550)

Bindungsspezifität: AA 37-760

Verwendungszweck: Anti-SEC63 Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SEC63 shares 96.1% amino acid (aa) sequence identity with mouse SEC63.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SEC63 recombinant protein (Position: R37-D760). Human SEC63 shares 96.1% amino acid (aa) sequence identity with mouse SEC63.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SEC63

Target: SEC63 (SEC63 Homolog (SEC63))

Andere Bezeichnung: SEC63

Hintergrund:

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Gene Full Name: SEC63 protein translocation regulator

Gen-ID: 11231

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling