SEC61B Antikörper (AA 16-96) (Fluoro594)

Produktnummer ABIN8034992

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SEC61B in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SEC61B Antikörper (AA 16-96) (Fluoro594) (ABIN8034992)

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC61B Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SEC61B Antikörper (Fluoro594)

Bindungsspezifität: AA 16-96

Verwendungszweck: Anti-SEC61B Antibody Fluoro594 Conjugated

Homologie: Human SEC61B shares 98.8% amino acid (aa) sequence identity with mouse SEC61B.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SEC61B recombinant protein (Position: R16-S96). Human SEC61B shares 98.8% amino acid (aa) sequence identity with mouse SEC61B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SEC61B

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Andere Bezeichnung: SEC61B

Hintergrund:

Background: Protein transport protein Sec61 subunit beta is a protein that in humans is encoded by the SEC61B gene. The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

Gene Full Name: SEC61 translocon subunit beta

Gen-ID: 10952

UniProt: P60468

Pathways: Protein targeting to Nucleus