SGCA Antikörper (AA 24-387) (HRP)

Produktnummer ABIN8034542

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SGCA in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SGCA Antikörper (AA 24-387) (HRP) (ABIN8034542)

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGCA Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SGCA Antikörper (HRP)

Bindungsspezifität: AA 24-387

Verwendungszweck: Anti-alpha Sarcoglycan/SGCA Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SGCA recombinant protein (Position: Q24-H387). Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SGCA

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Andere Bezeichnung: SGCA

Hintergrund:

Background: Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: sarcoglycan alpha

Sequence Similarities: Belongs to the sarcoglycan alpha/epsilon family.

Gen-ID: 6442

UniProt: Q16586