RNF8 Antikörper (AA 3-488) (Fluoro647)

Produktnummer ABIN8033370

Der Kaninchen Polyklonal anti-RNF8 Antikörper wird verwendet zum Nachweis von RNF8 in Proben von Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für RNF8 Antikörper (AA 3-488) (Fluoro647) (ABIN8033370)

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF8 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-RNF8 Antikörper (Fluoro647)

Bindungsspezifität: AA 3-488

Verwendungszweck: Anti-RNF8 Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse RNF8 recombinant protein (Position: E3-S488).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu RNF8

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Andere Bezeichnung: Rnf8

Hintergrund:

Background: E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.

Gene Full Name: ring finger protein 8

Gen-ID: 58230

UniProt: Q8VC56

Pathways: Production of Molecular Mediator of Immune Response