RING1 Antikörper (AA 6-387) (Fluoro488)

Produktnummer ABIN8033154

Der Kaninchen Polyklonal anti-RING1 Antikörper wird verwendet zum Nachweis von RING1 in Proben von Human und Ratte. Er wurde validiert für FACS.

Kurzübersicht für RING1 Antikörper (AA 6-387) (Fluoro488) (ABIN8033154)

Target: RING1 (Ring Finger Protein 1 (RING1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RING1 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-RING1 Antikörper (Fluoro488)

Bindungsspezifität: AA 6-387

Verwendungszweck: Anti-RING1 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human RING1 shares 96.3%,96.6% amino acid (aa) sequence identity with mouse,rat RING1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RING1 recombinant protein (Position: N6-K387). Human RING1 shares 96.3% and 96.6% amino acid (aa) sequence identity with mouse and rat RING1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Andere Bezeichnung: RING1

Hintergrund:

Background: E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Gene Full Name: ring finger protein 1

Gen-ID: 6015

UniProt: Q06587