RTKN2 Antikörper (AA 1-572) (Biotin)

Produktnummer ABIN8032293

Der Kaninchen Polyklonal anti-RTKN2 Antikörper wird verwendet zum Nachweis von RTKN2 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, WB und IHC.

Kurzübersicht für RTKN2 Antikörper (AA 1-572) (Biotin) (ABIN8032293)

Target: RTKN2 (Rhotekin 2 (RTKN2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTKN2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RTKN2 Antikörper (Biotin)

Bindungsspezifität: AA 1-572

Verwendungszweck: Anti-RTKN2 Antibody Biotin Conjugated

Homologie: Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RTKN2 recombinant protein (Position: M1-D572). Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RTKN2

Target: RTKN2 (Rhotekin 2 (RTKN2))

Andere Bezeichnung: RTKN2

Hintergrund:

Background: Rhotekin 2 is a protein in humans that is encoded by the RTKN2 gene. The RTKN2 gene encodes a protein known as Rhotekin-2, which is involved in various cellular processes, including cytoskeletal organization, cell migration, and signal transduction. RTKN2 interacts with Rho GTPases, particularly RhoA, and modulates their activity to regulate actin cytoskeleton dynamics and cell morphology. This protein plays a role in cell adhesion and migration, with implications for tissue development, wound healing, and cancer metastasis. Additionally, RTKN2 has been linked to synaptic plasticity and neuronal development in the brain. Dysregulation of RTKN2 expression or function has been associated with neurological disorders, cardiovascular diseases, and cancer progression. Elucidating the molecular mechanisms underlying RTKN2's diverse functions is crucial for understanding its physiological roles and its potential as a therapeutic target for various diseases.

Gene Full Name: rhotekin 2

Gen-ID: 219790

UniProt: Q8IZC4