Rhotekin Antikörper (AA 255-554) (Fluoro647)

Produktnummer ABIN8032291

Der Fluoro647-konjugierte Kaninchen Polyklonal anti-Rhotekin Antikörper (ABIN8032291) detektiert spezifisch Rhotekin in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rhotekin Antikörper (AA 255-554) (Fluoro647) (ABIN8032291)

Target: Rhotekin (RTKN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rhotekin Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Rhotekin Antikörper (Fluoro647)

Bindungsspezifität: AA 255-554

Verwendungszweck: Anti-RTKN Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RTKN recombinant protein (Position: R255-Q554).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Rhotekin

Target: Rhotekin (RTKN)

Andere Bezeichnung: RTKN

Hintergrund:

Background: Rhotekin is a protein that in humans is encoded by the RTKN gene. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: rhotekin

Gen-ID: 6242

UniProt: Q9BST9